Order Now: ⏩opioidstores.com⏮ Tramadol is a prescription pain medication that is used to treat moderate to severe pain. It is an opioid, which means that it works by binding to opioid receptors in the brain and spinal cord, which reduces the perception of pain. Tramadol is available in both immediate-release and extended-release formulations. The immediate-release formulation is taken every 4 to 6 hours as needed for pain relief.